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physiology

Mouse running on wheel
An Exercise-induced Liver Enzyme Boosts Metabolism
Natalia Mesa, PhD | Jul 7, 2023 | 3 min read
Exercise drives the liver to produce the CES2 enzyme, which circulates in blood and delivers some of the benefits of exercise in mice. 
A fluorescence microscopy image of placenta tissue made up of cells dyed blue, purple, pink and green on a black background.
The Cellular Intricacies of the Human Placenta
Ida Emilie Steinmark, PhD | Jul 5, 2023 | 2 min read
Rare samples saved 35 years ago helped researchers map gene expression and cell differentiation in first trimester placentas.
Learn How the Immune System Can Be Trained to Overcome Food Allergies
Retraining the Immune System Cavalry for Food Allergen Peacekeeping Missions
The Scientist’s Creative Services Team | 1 min read
Explore food allergy immunotherapy for reversing patient symptoms.
Brain cell in purple on a black background. Arc mRNAs are labeled green and are mainly localized in the cell nucleus and in the dendrites.
Short-lived Molecules Support Long-term Memory 
Alejandra Manjarrez, PhD | Jun 6, 2023 | 3 min read
A gene essential for information storage in the brain engages an autoregulatory feedback loop to consolidate memory.
EKG readout
The Circadian Rhythm of the Heart Rate
Katherine Paulin, PhD | May 31, 2023 | 3 min read
The sympathetic nervous system influences gene expression in the heart to regulate the day-night cycle of resting heart rate.
Peripheral blood mononuclear cells surrounded by red blood cells in circulating blood.
Accelerating Immune Research with Cryopreserved Peripheral Blood Mononuclear Cells
The Scientist’s Creative Services Team and MilliporeSigma | 3 min read
Commerically-available peripheral blood mononuclear cells offer a well-characterized, accessible, and consistent model for immunology and therapeutic development.
Side and front view of a male human skull
Mechanical Force on the Skull May Aid Bone Regeneration
Alejandra Manjarrez, PhD | May 1, 2023 | 3 min read
By mechanically inducing the expansion of cranial sutures in young adult mice, researchers stimulated stem cell proliferation that is key to healing bone injuries.
Green and brown illustration of cancer cells in front of a peach and yellow background.
Bacterial Tractor Beams Bring Radiation to Tumors
Rachael Moeller Gorman | Apr 17, 2023 | 3 min read
Colonizing tumors with engineered bacteria may allow researchers to target sites currently inaccessible to radionuclide therapy.
A Scientific Figure of Speech
Science Philosophy in a Flash - A Scientific Figure of Speech
Iris Kulbatski, PhD | 1 min read
Beate Peter shares how her “scientific bilingualism” is the driving force behind her philosophy of science.
Bear paw dusted in snow
Hibernating Bears Provide Clue to Preventing Serious Clots in Humans
Natalia Mesa, PhD | Apr 13, 2023 | 3 min read
Low levels of the clotting factor HSP47 protect the sleeping giants from blood clots, and the same may be possible for humans and other mammals.
Conceptual image of doctors and scientists analyzing and treating skin, with an emphasis on the hair follicle and skin layers.
Getting to the Root of Skin Healing
Iris Kulbatski, PhD | Apr 11, 2023 | 4 min read
The intimate link between hair follicles and wound healing is more than skin deep.
Exosomes, microvesicles, and apoptotic bodies: The three major types of extracellular vesicle.
Extracellular Vesicles: Applications and Potential
Beckman Coulter Life Sciences | 1 min read
Explore why extracellular vesicles are attractive candidates for new therapeutic approaches.
Education anatomy and Histological sample Striated (Skeletal) muscle of mammal Tissue under the microscope.
Mechanical Implant Stirs Wasting Muscle Back into Action
Holly Barker, PhD | Apr 3, 2023 | 3 min read
An implantable device stimulates muscle contraction and prevents muscular atrophy in mice.
Illustration showing an experimental device called MAGENTA and how it works
Infographic: Tissue Implant Gets Muscles Moving, Prevents Atrophy
Holly Barker, PhD | Apr 3, 2023 | 1 min read
The experimental device, known as MAGENTA, forces muscles to contract, simulating natural movement. 
Developing Aptamer Biosensor Technology for Diagnostics and Therapeutics
Expanding the Available Target Range for New Drugs and Diagnostics with Aptamers
The Scientist’s Creative Services Team and aptamer Group | 1 min read
In this roundtable discussion, an expert panel will discuss how the latest applications of aptamer technology are enabling innovation across the life sciences by replacing antibodies.
mouse
hCINAP Protein Key to Cellular Senescence: Study
Patience Asanga | Mar 23, 2023 | 3 min read
The authors claim that by preventing the formation of senescent cells, the protein could delay aging, but experts are skeptical.
Fluorescent image of breast tissue
Hormone Therapy Triggers Male Gene Patterns in Transgender Men’s Cells
Holly Barker, PhD | Mar 15, 2023 | 3 min read
A study deepens the scientific understanding of how androgens influence breast tissue, which may offer clues to treating breast cancer. 
Large-Scale Proteomics Drives Disease Research
Driving Disease Research and Therapeutics with Large-Scale Proteomics
The Scientist’s Creative Services Team and SomaLogic | 1 min read
Explore how technology enables large-scale proteomics for biomarker discovery and clinical application.
White mouse at the edge of a desk
The Heart Can Directly Influence Our Emotions
Natalia Mesa, PhD | Mar 1, 2023 | 4 min read
Researchers find that an increased heart rate can induce anxiety in mice, given the right context.
<em>We are Electric</em> book cover
The Skin Battery
Sally Adee | Mar 1, 2023 | 4 min read
The “wound current” has intrigued scientists for more than a century. It could turn out to be the key to healing catastrophic injuries.
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