cancer

Engineered bacteria sound the alarm on a common oncogenic mutation.

Researchers inhibited molecules that regulate both tumor and immune cell migration and their crosstalk signaling to impede metastasis.

Researchers at KU Leuven specialize in performing a multiplex immunohistochemistry method that uses conventional antibodies and pathologist-driven data analysis.

Editing epitopes expressed on the surfaces of transplanted hematopoietic stem cells renders them resistant to AML treatments without affecting their critical functions.

Researchers created a model that uses clinical testing data to locate the primary site of cancer cells with no known origin, likely improving survival.

Researchers integrate scRNA-seq, spatial transcriptomics, and histology imaging data to show that spatial cellular architecture predicts glioblastoma prognosis.

Anne L’Huillier, Pierre Agostini, and Ferenc Krausz received this year’s Physics award for creating tools for studying the world of electrons, with future applications in medical diagnostics.

An often overlooked property of the tumor environment shapes T cell function and may improve T cell therapies.

Vaginal dysbiosis has long been a taboo subject, but studying and optimizing the vaginal microbiome could be a game changer for women's health.

Researchers studying lung cancer cell lines found that chromatin remodeling underlies one type of osimertinib resistance.

Researchers unravel the mystery of epithelial to mesenchymal transition in acute lymphoblastic leukemia with co-culture techniques, CRISPR-screening, and RNA sequencing.

Scientists established an epigenetic mouse model for glioma, providing insight into how epigenetics can initiate cancer.

This year’s Breakthrough Prizes honor advances in CAR T cancer therapies, cystic fibrosis, and Parkinson’s disease.

Researchers took aim at mucins, glycoproteins that protect cancer cells from drugs and the immune response, and engineered a revolutionary targeted tool for oncology and beyond.