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Tumors being attacked by cytotoxic T cells.
A microRNA Family Drives the T Cell Response in Cancer
When their in vitro and in vivo results conflicted, researchers took a deep dive into microRNAs’ influence on T cell memory formation.
A microRNA Family Drives the T Cell Response in Cancer
A microRNA Family Drives the T Cell Response in Cancer

When their in vitro and in vivo results conflicted, researchers took a deep dive into microRNAs’ influence on T cell memory formation.

When their in vitro and in vivo results conflicted, researchers took a deep dive into microRNAs’ influence on T cell memory formation.

transcriptome

3D image of a neuron cell network with a red glow representing inflammation.
New Insight into Brain Inflammation Inspires New Hope for Epilepsy Treatment 
Deanna MacNeil, PhD | Jun 1, 2023 | 2 min read
Clinicians and researchers teamed up to investigate how inappropriate proinflammatory mechanisms contribute to the pathogenesis of drug-refractory epilepsy.
An artist’s rendition of transcription inside a nucleus
Hypertranscription by Tumors Is Linked to Poorer Cancer Outcomes: Study
Sophie Fessl, PhD | Dec 13, 2022 | 3 min read
The extent to which transcription is higher in tumor cells than in surrounding nontumor cells is associated with bad prognoses in several cancer types.
Learn About Customizing Gene Expression Experiments
A How-to Guide for Planning Single Cell Gene Expression Studies
10x Genomics | Oct 21, 2022 | 1 min read
Follow the roadmap to successful single cell transcriptomic workflows and outputs.
Developing Spatial Multiomic Maps
Technique Talk: Developing Spatial Multiomic Maps
The Scientist’s Creative Services Team | Aug 29, 2022 | 1 min read
Rafael Kramann will discuss spatial transcriptome and epigenome changes to identify injury, repair, and remodeling in myocardial infarction.
Histological slide showing cancerous prostate tissue
2D Genetic Map of Prostate Cells Charts Cancer Growth
Holly Barker, PhD | Aug 23, 2022 | 4 min read
An in situ map of copy number variations in prostate tissue reveals that purportedly cancerous genomic changes frequently occur in the healthy tissue surrounding tumors.
scanning electron microscope image of clawlike microscopic organisms on a smoother surface
Phyla of Tiny Filter Feeders Find a New Spot on the Tree of Life
Alejandra Manjarrez, PhD | Jul 6, 2022 | 5 min read
A new study using fairly complete genetic datasets of two phyla of small suspension feeders (Ectoprocta and Entoprocta) reopens the debate on the phylogenetic relationships between them and other animals.
Ribonucleic acid strands consisting of nucleotides important for protein bio-synthesis
Katharina Höfer Probes the Machinery of Bacterial Gene Expression
Hannah Thomasy, PhD | Jun 13, 2022 | 3 min read
The molecular biologist studies how chemical modifications to RNA building blocks change the way RNA regulates complex cellular processes.
Select the Right Assay to Assess Gene Expression
How to Select the Right Assay for Gene Expression Studies
Canopy Biosciences | Feb 23, 2022 | 1 min read
Six key questions help researchers determine the right approach for a given gene expression study.
Key Genes Related to Severe COVID-19 Infection Identified
Max Kozlov | Dec 14, 2020 | 3 min read
Differences in the expression of genes associated with antiviral immunity and lung inflammation may contribute to a more serious COVID-19 infection.
Identified: Molecular Predictors of Rheumatoid Arthritis Relapse
Ruth Williams | Jul 15, 2020 | 4 min read
The presence of a particular set of RNAs in the blood forewarns of an onset of severe symptoms and points to the cells involved.
Worm Embryogenesis: Cell by Cell and Gene by Gene
Kerry Grens | Dec 1, 2019 | 2 min read
A single-cell map of C. elegans’s transcriptome during development finds cell lineages that start out genetically different and end up as cells of similar function and genetic profile.
Increased Neuronal Activity Shortens Lifespan in Animals
Ruth Williams | Oct 16, 2019 | 3 min read
Suppressing the natural age-related increase in neuronal excitation lengthens the lives of worms, and there are indications that the same may be true for mice and humans.
Hydra single-cell sequencing gene expression
Image of the Day: Expressive Hydra
Nicoletta Lanese | Jul 26, 2019 | 1 min read
Researchers track which genes are active in the polyp during successive cell states.
Gene Expression Overlaps Among Psychiatric Disorders
Ashley P. Taylor | Feb 8, 2018 | 3 min read
Transcriptional profiling of post-mortem human brains reveals commonalities in the genes over- and under-expressed in schizophrenia, bipolar disorder, autism, and major depression. 
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