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Turning to molecular genetics, the Baylor pediatric neurologist and geneticist works to discover the biological basis for the rare neurological diseases she sees in her patients.

Lampbrush chromosomes, first observed in the 19th century, still offer an unparalleled glimpse into how genetic information is organized in the cell.

Pauses may help cells fine-tune gene expression.

Researchers are just beginning to scratch the surface of how several newly recognized epigenetic changes function in the genome.

To expand the basic nucleotide alphabet, many species modify their DNA with epigenetic marks.

Our guide to all known forms of RNA, from cis-NAT to vault RNA and everything in between.

Scientists discover transcripts from the same gene that can express both proteins and noncoding RNA.
 

Through similar mechanisms, amino acid depletion in culture and cytokine activity in the tumor microenvironment prompt cancer cells to metastasize.

Genes linked to embryonic development, stress, and cancer are increasingly transcribed into RNA after these animals die.

See how researchers visualize regions of active genes.

Solving a long-standing structural puzzle will open the door to understanding one of the cell’s most enigmatic machines.

Some ciliates use the same trio of nucleotides to code for an amino acid and to stop translation.

Four independent research groups develop techniques for visualizing peptide production in living cells.

Traditional stop codons have a double meaning in the protozoans' mRNA, sometimes calling for an amino acid during translation.

Researchers have designed a screen to find unique molecules, called riboswitches, that determine whether transcription will proceed.

A newly developed method detects regulators of bacterial transcription called riboswitches.

Endurance exercise and metabolism are linked to transcriptional activation of human telomeres, researchers propose.

From whole cells to genes, closer examination continues to surprise.
 

Newer CRISPR tools for manipulating transcription will help unlock noncoding RNA’s many roles.

Susan Lindquist has never shied away from letting her curiosity guide her research career.