New tools for tracking changes in gene expression with spatiotemporal precision could illuminate mechanisms driving development or disease progression. Inspired by the history recorded in tree rings, researchers developed a novel technology that records transcriptional events as fluorescent tags onto elongating protein chains embedded inside cells.1

     Diagram tracking changes in gene expression
DESIGNED BY ERIN LEMIEUX

References

  1. Lin D, et al. Nat Biotechnol. 2023;41:631-639.
  2. Baskaran Y, et al. Nat Commun. 2015;6:8681.