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A microRNA Family Drives the T Cell Response in Cancer
A microRNA Family Drives the T Cell Response in Cancer
When their in vitro and in vivo results conflicted, researchers took a deep dive into microRNAs’ influence on T cell memory formation.
When their in vitro and in vivo results conflicted, researchers took a deep dive into microRNAs’ influence on T cell memory formation.
mouse model
Reversing Hearing Loss
Laura Tran, PhD | Nov 1, 2023 | 2 min read
Gene reactivation restored hearing after loss in mice, but the timing of intervention is key.
Stem Cells Breathe New Life into Lungs
Aparna Nathan, PhD | Oct 30, 2023 | 3 min read
New studies proposed using stem cells to make long-lasting lung grafts.
The Scientist’s Journal Club: Olfaction and the Brain
The Scientist’s Creative Services Team | 1 min read
Gonzalo Otazu will discuss how the brain processes smells differently in neurotypical mice compared to a mouse model of autism spectrum disorder.
Spectral Flow Cytometry: Separating the Fluorophore Rainbow
Charlene Lancaster, PhD | Oct 24, 2023 | 3 min read
Spectral flow cytometry separates similarly emitting fluorophores and enabled Kaitlyn Sadtler to construct a 24-color rat panel for immunological analyses.
Differentiated Stem Cells Can Kickstart Fertility in Mice
Aparna Nathan, PhD | Oct 23, 2023 | 3 min read
Ovarian cells derived from stem cells restore hormones and cells needed to produce pups.
Understanding Hybridoma Technology for Monoclonal Antibody Production
Alpana Mohta, MD | 5 min read
By fusing antibody-producing cells with immortal myeloma cells, researchers produce reliable supplies of highly specific antibodies.
Targeting Breast Cancer Metastasis
Tanvir Khan, PhD | Oct 16, 2023 | 3 min read
Researchers inhibited molecules that regulate both tumor and immune cell migration and their crosstalk signaling to impede metastasis.
A Long and Unhealthy Life?
Aparna Nathan, PhD | Sep 13, 2023 | 3 min read
A new mouse model shows that the Myc protein has complex effects on aging and cancer.
Contract Vivarium Facilities for Preclinical Discovery
The Scientist’s Creative Services Team and Mispro | 3 min read
Researchers rent contract vivarium space for greater experimental control, productivity, and reproducibility when developing new therapeutics.
Bladder ‘Memory’ Influences Urinary Tract Infection Recurrence in Mice
Alejandra Manjarrez, PhD | Apr 12, 2023 | 3 min read
Urinary tract infections leave permanent epigenetic marks in the mouse bladder epithelium, reprogramming its response to subsequent infections, a study finds.
How Cells in the Skin Team Up To Fight Pathogens
Rachael Moeller Gorman | Apr 12, 2023 | 4 min read
Immune cells and pain neurons form complex partnerships to protect our bodies from pathogens, new research reveals.
Brush Up: Humanized Mice: More than the Sum of Their Parts
Deanna MacNeil, PhD | 5 min read
Scientists study human health in vivo with modified mice that molecularly mimic human biology.
Self-Charging Battery Battles Tumors in Mice
Natalia Mesa, PhD | Apr 4, 2023 | 3 min read
A battery that charges itself in salty fluids starves tumors of oxygen, helping improve some drugs treat cancer, a study finds.
Drugs Hitch a Ride on Algae for Targeted Delivery
Holly Barker, PhD | Feb 1, 2023 | 3 min read
A new microrobot uses algae to transport antibiotics into the lungs of mice with pneumonia.
The Scientist Speaks - Virulence Meets Metabolism: The Unique Evolution of Staphylococcus aureus
Niki Spahich, PhD | 1 min read
Anthony Richardson discusses what makes Staph especially dangerous for people with diabetes.
Infographic: Algae Robots Transport Antibiotics to Infected Tissues
Holly Barker, PhD | Feb 1, 2023 | 1 min read
Microscopic algae dotted with drug-filled nanoparticles may offer a more effective means of treatment than traditional delivery methods.
Opioids Recruit the Immune System to Cause Withdrawal Symptoms
Dan Robitzski | Jan 25, 2023 | 6 min read
A study finds that T cells induced by heroin cross the blood-brain barrier to wreak havoc on the brain, hinting at new ways to prevent withdrawal.
LabTalk Podcast - A Modern Trojan Horse: Delivering Combination Immunotherapies to Solid Tumors
The Scientist’s Creative Services Team and IsoPlexis | 1 min read
Katie McKenna discusses a combination CAR T and viral therapy that kills solid tumors.
Asthma Drug Helps Mice Retrieve Memories “Lost” to Sleep Deprivation
Zunnash Khan | Jan 24, 2023 | 4 min read
A study finds roflumilast can reverse sleep deprivation–induced amnesia in mice, hinting at pathways to treating memory loss in people.