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CRISPR

Hannah Thomasy, PhD | Nov 1, 2023 | 4 min read

Engineered bacteria sound the alarm on a common oncogenic mutation.

Venus flytrap plants grow in the lab, trigger hairs at the ready.

Rachael Moeller Gorman | Oct 16, 2023 | 4 min read

Scientists used CRISPR-Cas9 for the first time in a carnivorous plant to prove the role of two ion channels in closing the Venus flytrap’s trap.

<em >The Scientist</em>’s Journal Club: Detecting Nucleic Acids with CRISPR

The Scientist’s Journal Club: Detecting Nucleic Acids with CRISPR

The Scientist’s Creative Services Team | 1 min read

Kuangwen Hsieh will discuss his research understanding CRISPR-based nucleic acid detection assays.

A three-dimensional rendered image of neuron cell network on black background.

Assembloids Unlock the Roles of Key Neurodevelopment Disease Genes

Aparna Nathan, PhD | Sep 27, 2023 | 3 min read

Brain-like tissue grown in a dish mimics critical periods for development and reveals how it can go wrong.

Image of <em >Candida albicans</em> fungus.

A Fungus Plays Tug-of-war for Metal Ions

Laura Tran, PhD | Sep 14, 2023 | 3 min read

In the fight between hosts and fungal pathogens, scientists discovered how withholding manganese can cripple Candida albicans.

Targeting a Genetic Accident to Treat Disease

Deanna MacNeil, PhD | 2 min read

David Liu shares how integrating chemistry and evolution in his research has directed his work on base editing techniques aimed at developing new therapeutics.

This shows a cryo-EM map of a Fanzor protein in complex with its guiding RNA (in purple) and DNA (target strand in red, complementary strand in blue).

CRISPR-like Abilities in Eukaryotic Proteins

Ida Emilie Steinmark, PhD | Sep 8, 2023 | 4 min read

Two groups independently discovered that Fanzor proteins in eukaryotic organisms are CRISPR’s genome-editing cousins.

A dart board with on dart on the bullseye and several scattered darts that missed the target

Predicting the Next Level of CRISPR Control

Deanna MacNeil, PhD | Aug 28, 2023 | 3 min read

Scientists combine the power of genome-wide screens and machine learning to unlock the secrets of transcriptome engineering with Cas13.

Versatile and Sustainable: Cell Counting for the 21^st Century

The Scientist’s Creative Services Team and DeNovix Inc. | 3 min read

Discover how the latest cell counting technology is reshaping a mundane task for the future.

Blood vessel with flowing red blood cells and white immune cells.

New CRISPR Treatment Could Prevent HIV Reinfection after Viral DNA Excision

Jennifer Zieba, PhD | Aug 21, 2023 | 3 min read

Researchers design dual CRISPR treatments to remove HIV DNA and prevent reinfection in vitro.

A transverse section of stem wood from the researchers’ greenhouse-grown poplar tree.

CRISPR Trees Could Improve Paper Production

Alejandra Manjarrez, PhD | Aug 15, 2023 | 3 min read

Researchers edited several tree genes to improve suitability and sustainability in the pulp and paper industry.

COVID-19: Lessons Learned

The Scientist’s Creative Services Team | 2 min read

An expert panel will discuss what researchers have learned from the COVID-19 pandemic and what lessons remain for the future.

Photo of Rosa Bacchetta, associate professor of pediatrics at Stanford University

The Future of Gene Therapy for a Rare Pediatric Autoimmune Disease

Niki Spahich, PhD | Jul 10, 2023 | 3 min read

By editing a mutated immune regulatory gene in patient cells, Rosa Bacchetta brings hope to those suffering from IPEX syndrome.

Immunity Genes May Play a Role in Down Syndrome

Kamal Nahas, PhD | Jul 6, 2023 | 4 min read

Extra copies of four interferon receptor genes found on human chromosome 21 trigger developmental changes in a mouse model of Down syndrome.

3d render illustration of Single strand ribonucleic acid.

Message in a Bottle: Developing mRNA Therapeutics

The Scientist’s Creative Services Team and Mirus Bio | 3 min read

A high efficiency, low toxicity method for direct RNA delivery into cells.

Glow-in-the-dark Diagnostics

Danielle Gerhard, PhD | Jul 5, 2023 | 2 min read

A nucleic acid detection platform that marries CRISPR diagnostic tools with bioluminescence could accelerate treatment decisions in the clinic.

Redesigning Medicine Using Synthetic Biology

Alison Halliday, PhD, Technology Networks | Jun 21, 2023 | 5 min read

Drawing inspiration from nature, synthetic biology offers exciting opportunities to transform the future of medicine.

Technique Talk: Understanding Cancer One Base Edit at a Time

The Scientist’s Creative Services Team | 1 min read

Francisco J. Sánchez-Rivera will discuss strategies to design CRISPR base editor libraries for in vivo applications.

Combating Mosquito-Borne Diseases with CRISPR

Niki Spahich, PhD | Jun 1, 2023 | 4 min read

As alternatives to insecticides, Omar Akbari uses sophisticated genetic engineering methods to solve the world’s mosquito problems.