cancer genomics

Computational biologist Jinghui Zhang of St. Jude realized scientists could work more efficiently with tools and genomic data shared on the cloud.

In the largest study of its kind to date, researchers find more than 850 rare, heritable genetic alterations that can predispose humans to cancer.

Two large-scale studies reveal new insights into the genomic characteristics of childhood cancers.

China shows the biggest increase of any country in the number of scientists listed since last year, while cancer genomics emerges as one of the more dominant fields.

The publicly available database found nearly a third of samples included mutations targeted by either approved drugs or therapies in clinical trials. 

At the University of California, Santa Cruz, the researcher combs the cancer genome, looking for weaknesses.

April Scientist to Watch Angela Brooks of the University of California, Santa Cruz, discusses her search to find vulnerabilities buried within the genomes of cancer cells.

The genomics pioneer shares the sessions she most looks forward to at this year’s American Association for Cancer Research annual meeting.

Some doctors advise shoppers to be skeptical of a newly marketed cancer diagnostic.

An algorithm can pick out biologically and clinically meaningful variants from whole-exome sequences of tumors.

The IBM supercomputer, famous for its game show performance, will aid in cloud-based analyses of genomic data.  

Sage Bionetworks aims to show that transparency and sharing are key to ensuring research reproducibility.

A new study finds strong evidence that bacteria can transfer genes into human genomes, especially in cancer cells.

Researchers reveal why analyses of cancer-causing mutations are riddled with false positives and demonstrate a new approach that eliminates the problem.

Hot topics from the AACR meeting; the ongoing debate about pesticides’ effects on bees; a treasure trove of baby dinos; conservation on social media

This month’s AACR attendees, including National Cancer Institute Director Harold Varmus, discuss new approaches to cancer research using whole genome sequencing.

By scrutinizing gene expression profiles instead of individual oncogenes, Todd Golub launched a powerful platform for diagnosing, classifying, and treating cancer.

Advances in genomics and cancer biology will alter the design of human cancer studies.

A decade into the age of genomics, science is generating a flood of data that will help in the quest to eradicate the disease.

Researchers are taking advantage of small, transparent zebrafish embryos and larvae—and a special strain of see-through adults—to understand the development and spread of cancer.