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biochemistry

This shows a cryo-EM map of a Fanzor protein in complex with its guiding RNA (in purple) and DNA (target strand in red, complementary strand in blue).
CRISPR-like Abilities in Eukaryotic Proteins
Ida Emilie Steinmark, PhD | Sep 8, 2023 | 4 min read
Two groups independently discovered that Fanzor proteins in eukaryotic organisms are CRISPR’s genome-editing cousins.
Erkin Kuru (left) and Helena de Puig (right).
Lighting Up Diagnostics
Danielle Gerhard, PhD | Sep 8, 2023 | 6 min read
Brought together by a shared interest in synthetic biology and diagnostics, two researchers are transforming how we label biomolecules.
Discover how a cellphone-driven UV gel documentation system accelerates accessible imaging.
Accessible Gel Imaging with a Cellphone
Analytik Jena | 1 min read
In the classroom or the laboratory, a new gel documentation system enables scientists to capture snapshots of their samples in real time.
A yellow, hairy caterpillar is sitting on a green leaf off a thin plant stem.
Deciphering Plants’ Biochemical Messages
Ida Emilie Steinmark, PhD | Sep 1, 2023 | 2 min read
Esther Ngumbi believes that chemical signals between plants, microbes, and insects hold the key to secure and sustainable food production.
A 96-well microplate containing serial dilutions of stained samples.
Expanding Sample Analysis While Shrinking Instrument Footprints
The Scientist Staff | Sep 1, 2023 | 2 min read
Cutting-edge analytical instruments provide researchers with improved analysis capabilities in a compact design.
A photo of a scientist working with an EpMotion® liquid handler.
Simplifying Liquid Handling Workflows with Automation
The Scientist’s Creative Services Team and Eppendorf | 3 min read
Learn about the legacy of liquid handling in molecular breakthroughs and how effortless automation enables more accurate and precise research processes.
Illustration showing how this new novel nanotechnology simultaneously ‘fishes’ for multiple viruses or viral variants using different DNA nanobait that are designed to target specific viral sequences.
Fishing for Viruses With DNA Nanobait
Danielle Gerhard, PhD | Sep 1, 2023 | 2 min read
Scientists developed a novel nanotechnology that simultaneously detects multiple viruses from patient samples in less than an hour.
Oops, speech bubble.
The Oligo Was a No Go
Danielle Gerhard, PhD | Sep 1, 2023 | 2 min read
As soon as Melanie McConnell added the wash buffer to her sample, she knew she had made a mistake.
A 3D rendering of an albumin’s protein structure.
Providing Stability In Vivo, In Vitro, and In Culture
The Scientist’s Creative Services Team and MilliporeSigma | 3 min read
Albumins enable researchers to bind, sequester, and stabilize important molecules across research applications.
Conceptual image of hair loss showing trees in the shape of a human head at various seasonal stages of shedding their leaves.
Islands of Knowledge: Hairy Skin Moles Make Their Mark
Iris Kulbatski, PhD | Aug 7, 2023 | 3 min read
Skin moles that sprout thick, long hairs produce signaling molecules that stimulate hair follicle stem cells to initiate new hair growth. This discovery may make baldness a thing of the past.
 Dive into Cryo-EM’s History, Milestones, and Insights.
Cryo-EM: Building on a History of Invention and Innovation
Thermo Fisher Scientific | Aug 2, 2023 | 1 min read
From humble yet ingenious beginnings to Nobel recognition, cryogenic electron microscopy (cryo-EM) provides insights into scientific questions that other technologies are unable to answer.
Lipofuscin autofluorescence was quenched using EverBrite TrueBlack® Hardset Mounting Medium®, allowing effective visualization of glial cells (GFAP antibody stain, cyan) and cell nuclei (magenta) in human cerebral cortex cryosections.
Stepping Out of the Background
The Scientist’s Creative Services Team and Biotium | 4 min read
New developments in non-specific fluorescence quenching offer researchers clearer pictures and more multiplexing possibilities.
Image of unfolded protein
My Protein Didn't Fold and Neither Did I
Meenakshi Prabhune, PhD | Aug 1, 2023 | 2 min read
When Gaurav Ghag realized that he had replicated a calculation error in every experiment during four years of his graduate research, he initially thought that his career had unraveled with his protein.  
Image of coral reef
A Probiotic to Protect Caribbean Corals
Mariella Bodemeier Loayza Careaga, PhD | Aug 1, 2023 | 2 min read
A bacterial strain from healthy corals could slow the progression and prevent transmission of the destructive stony coral tissue loss disease in the wild.
The Ins and Outs of LC-MS
The Ins and Outs of LC-MS
Deanna MacNeil, PhD | 4 min read
From proteomics to pharmacokinetics, researchers turn to advances in liquid chromatography and mass spectrometry to identify and quantify components in different samples.
Green-themed conceptual illustration of a human profile with abstract patterns that represent smelling.
Disease Scent Signatures Disclose What the Nose Knows
Iris Kulbatski, PhD | Jun 12, 2023 | 4 min read
Researchers redefine the lost art of smelling illness using one woman’s exquisitely sensitive nose.
Saccharomyces cerevisiae 
Waves of Macromolecule Production During the Cell Cycle
Mariella Bodemeier Loayza Careaga, PhD | Jun 1, 2023 | 3 min read
In individual yeast cells, essential biosynthetic processes peak at different times in the cell cycle, revealing a temporal dynamic once thought limited to DNA synthesis.
The Intricacies of Western Blotting
The Intricacies of Western Blotting
The Scientist’s Creative Services Team | 1 min read
In this webinar, R. Hal Scofield discusses hints and tips on how to generate clean and reproducible western blot data, even in tricky situations. 
a yellow-ish fish skull is held up by metal prongs, with a rack of other museum collection items in the background
Fossilized Fish Teeth Could Be Earliest Evidence of Cooking
Katherine Irving | Nov 14, 2022 | 2 min read
Study authors say the teeth, dated around 780,000 years old, push back the date humans are known to have engaged in cooking by more than 600,000 years. 
Rows of soybean plants with green leaves beneath a partially clouded sky with the rising sun in the background.
As Carbon Dioxide Goes Up, Plants’ Nutrient Content Declines
Dan Robitzski | Nov 3, 2022 | 5 min read
Abundant environmental CO2 can increase plant biomass and photosynthesis, but it has downsides for agriculture and ecosystems, a growing body of research finds.
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